Genetic association between IL-27 rs153109 polymorphism and cancer risk in Chinese population: a meta-analysis
نویسندگان
چکیده
منابع مشابه
IL-27 rs153109 polymorphism increases the risk of colorectal cancer in Chinese Han population
IL-27, a new member of the IL-12 family, has been found to have antitumor effects in colorectal cancer (CRC); therefore, polymorphisms of this protein may modulate CRC carcinogenesis. So, we studied the association of single nucleotide polymorphisms of the IL-27 gene with the risk of CRC occurrence using a case-control using 600 CRC patients and matched healthy controls. The IL-27 rs153109 poly...
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Several studies examined the relationship between STAT3 rs1053004 polymorphism and the risk of some human cancers, but the findings remains inconclusive. To evaluate the impact of STAT3 rs1053004 on cancer risk, we conducted a meta-analysis of all available studies including 4,605 cancer cases and 5,248 controls. Eligible studies were identified by searching PubMed, Web of Sci...
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Non-small-cell lung cancer (NSCLC) has a multifactorial pathogenesis, and the genetic background may be one of the critical etiologic factors. Interleukin (IL)-27, a novel member of the IL-12 family, plays a vital role in antitumor immunity. The aim of the current study was to determine the association of a single nucleotide polymorphism of the IL-27 gene with the risk of NSCLC. The genotype of...
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Objective: To perform a 1:1 matched case-control study to evaluate the role of IL-8 rs4073, rs1126647 and rs2227306 polymorphisms in the development of ovarian cancer in a population of China. Methods: A total of 280 patients with ovarian cancer and 280 healthy controls were recruited. Genotyping of IL-8 rs4073, rs1126647 and rs2227306 were run in a 384-well plate format on the sequenom MassARR...
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ژورنال
عنوان ژورنال: Journal of Receptors and Signal Transduction
سال: 2017
ISSN: 1079-9893,1532-4281
DOI: 10.3109/10799893.2014.986743